Stimulant drugs for ADHD in school settings: methylphenidate 30/70

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Published

2013-03-12

How to Cite

Pelaz, A., Mardomingo, M. J., Herreros, O., Rodríguez Hernández, P. J., Gastaminza, X., Muñoz, A. M., & Plaza, S. (2013). Stimulant drugs for ADHD in school settings: methylphenidate 30/70. Revista De Psiquiatría Infanto-Juvenil, 30(1), 16–26. Retrieved from https://aepnya.eu/index.php/revistaaepnya/article/view/259

Issue

Vol. 30 No. 1 (2013)

Section

Review article

Authors

  • Antonio Pelaz Hospital Clínico (Madrid)
  • María Jesús Mardomingo Hospital Universitario Gregorio Marañón (Madrid)
  • Oscar Herreros Hospital Universitario Virgen de las Nieves (Granada)
  • Pedro Javier Rodríguez Hernández Hospital Universitario Ntra. Sra. de Candelaria
  • Xavier Gastaminza Hospital Vall d’Hebron (Barcelona)
  • Antonio Manuel Muñoz Shire Pharmaceuticals
  • Sylvia Plaza Departamento Médico, Shire Pharmaceuticals

Keywords:

ADHD, Attention Deficit Hyperactivity Disorder

Abstract

Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common psychiatric disorders in childhood, with an overall accumulated prevalence around 5%. It is characterized by the presence of symptoms such as inattention, impulsivity and hyperactivity. Children with ADHD show difficulties from an early age in focusing attention, control of impulsiveness and modulation of behavior. Clinical evidence suggests that, unless they reach a minimum of social competence at 8 years of age, these children will have a high probability of having social difficulties throughout his life. Treatment of ADHD consists of several strategies combined (multimodal treatment), where pharmacotherapy is prominent under different clinical practice guidelines. In the school environment, the goals of ADHD treatment focus on child adaptation to social and academic requirements by reducing the impact of core symptoms. Methylphenidate has proved effective with an adequate safety profile. Their release profile is correlated with the clinical efficacy and hence a release profile uniformly covering the 8 school hours as methylphenidate 30/70 is effective throughout the school day.

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Author Biographies

Pedro Javier Rodríguez Hernández, Hospital Universitario Ntra. Sra. de Candelaria

Hospital de Día Infantil y Juvenil “Diego Matías Guigou y Costa”. Servicio de Psiquiatría. Hospital Universitario Ntra. Sra. de Candelaria. Tenerife

Antonio Manuel Muñoz, Shire Pharmaceuticals

Departamento Médico, Shire Pharmaceuticals

Correspondencia:
Antonio Manuel Muñoz
amunoz@shire.com
Avda. Partenon, 16-18, 4ª Planta
28042 Madrid (España)

References

Polanczyk, de Lima, Horta, Biederman, Rohde LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 2007; 164 (6): 942-8.

American Psychiatric Association [DSM-IV-TR], 2000.

CIE-10: ICD-10 copyright © 1992 by World Health Organization.

A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Multimodal Treatment Study of Children with ADHD. MTA cooperative Group. Arch. Gen Psychiatry 1999: 1088-1096.

Barkley, R. A. (2006). Attention deficit hyperactivity disorder: A handbook for diagnosis and treatment (3rd ed.).

Guilford Press, Goldman LS, Genel M, Bezman RJ, Slanetz PJ. Diagnosis and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Council on Scientific Affairs, American Medical Association. JAMA. 1998; 279: 1100–1107.

Cardo E, Servera M, Llobera J. Estimation of the prevalence of attention defi cit hyperactivity disorder among the standard population on the island of Majorca. Rev Neurol. 2007 1; 44 (1): 10-4.

Benjumea P, Mojarro MA. Trastornos hipercinéticos: estudio epidemiológico en doble fase de una población sevillana. Anales de Psiquiatría. 1993; 9 (7): 306-11.

Scheffler RM, Brown TT, Fulton BD, Hinshaw SP, Levine P, Stone S. Positive Association Between Attention-Deficit/ Hyperactivity Disorder Medication Use and Academic Achievement During Elementary School. Pediatrics 2009; 123: 1273.

Guía de Práctica Clínica sobre el Trastorno por Déficit de Atención con Hiperactividad (TDAH) en Niños y Adolescentes. Ministerio Sanidad, Política Social e Igualdad. 2010.

National Institute for Health and Clinical Excellence. Attention deficit hyperactivity disorder. Diagnosis and management of ADHD in children, young people and adults. Great Britain: The British Psychological Society and The Royal College of Psychiatrist; 2009.

Mannuzza S, Klein RG, Bessler A, Malloy P, Hynes ME. Educational and occupational outcome of hyperactive boys grown up. J Am Acad Child Adolesc Psychiatry 1997; 36:1222–1227.

CHILD MENTAL HEALTH AND HUMAN CAPITAL ACCUMULATION: THE CASE OF ADHD Janet Currie Mark Stabile http://www.nber.org/papers/w10435.

McGee, R. Williams, S. Feehan, M. Attention deficit disorder and age of onset of problem behaviors. Journal of Abnormal Child Psychology 1992; 20: 487–502.

McGee, R., Prior, M., Williams, S. The long-term significance of teacher-rated hyperactivity and reading ability in childhood: findings from two longitudinal studies. The Journal of Child Psychology and Psychiatry 2002; 43: 1004–1017.

School Functioning of Students With ADHD: Du-Paul School Psychology Review,2007, Volume 36, No. 2, pp. 183–194.

Blair, C.,Diamond, A.. Biological processes in prevention and intervention: The promotion of selfregulation as a means of preventing school failure. Development and Psychopathology (2008), 20(3), 899-911.

Duncan, G. J., Dowsett, C. J., Claessens, A., Magnuson, K., Huston, A. C., Klebanov, P., et al. (2007). School readiness and later achievement. Dev Psychol, 43(6), 1428-1446.)

Loe, I.M.,Feldman, H.M. Academic and educational outcomes of children with ADHD. J Pediatr Psychol. 2007 Jul;32(6):643-54. Epub 2007 Jun 14

Barry, R. J., Clarke, A. R., McCarthy, R., Selikowitz, M. EEG coherence in attention-deficit/ hyperactivity disorder: a comparative study of two DSM-IV types. Clin Neurophysiol, (2002);113(4), 579-585.,

Biederman, J., Faraone, S., Milberger, S., Guite, J., Mick, E., Chen, L., et al. A prospective 4-year follow-up study of attention-deficit hyperactivity and related disorders. Arch Gen Psychiatry 1996., 53(5), 437-46)

Barkley, R.A., Fischer, M, Edelbrock, C.S., & Smallish, L. (1990). The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study. J Am Acad Child Adolesc Psychiatry. Jul;29(4):546-57)

Mannuzza, S., Klein, R.G., Bessler, A., Malloy, P. LaPadula, M. Adult outcome of hyperactive boys. Educational achievement, occupational rank, and psychiatric status. Arch Gen Psychiatry, 1993; 50(7), 565-76.)

Hinshaw, S.P. (1992). Academic underachievement, attention deficits, and aggression: comorbidity and implications for intervention. J Consult Clin Psychol, 60(6), 893-903.

Rapport, M.D, Scanlan, S.W., Denney, C.B. Attention-deficit/hyperactivity disorder and scholastic achievement: a model of dual developmental pathways. J Child Psychol Psychiatry, 1999; 40(8), 1169-1183).

Jensen PS, Garcia JA, Glied S, Crowe M, Foster M, Schlander M. Cost-Effectiveness of ADHD Treatments: Findings from the Multimodal Treatment Study of Children With ADHD. Am J Psychiatry 2005; 162: 1628-1636.

Barbaresi WJ, Katusic SK, Colligan RC, Weaver AL, Jacobsen SJ: Modifiers of long term school outcomes for children with Attention- deficit/Hyperactivity Disorder: Does treatment with stimulant medication make a difference? Results from a population- based study. J Develop Behav Pediatr 2007; 28: 274–287.

Powers RL, Marks DJ, Miller CJ, Newcorn JH, Halperin JM. Stimulant Treatment in Children with Attention-Deficit/Hyperactivity Disorder Moderates Adolescent Academic Outcome. J Child Adolesc Psychopharmacol. 2008; 18 (5): 449-59.

Zoëga H, Rothman KJ, Huybrechts KF, Ólafsson Ö, Baldursson G, Almarsdóttir AB et al. A Population- Based Study of Stimulant Drug Treatment of ADHD and Academic Progress in Children. Pediatrics. 2012; 130 (1): e53-62.

Loe IM, Feldman HM. Academic and Educational Outcomes of Children With ADHD. J Pediatr Psychol. 2007; 32 (6): 643-54.

Evans SW, Pelham WE, Smith BH, Bukstein O, Gnagy EM. Dose-response effects of methylphenidate on ecologically valid measures of academic performance and classroom behavior in adolescents with ADHD. Exp Clin Psychopharmacol. 2001; 9 (2): 163-75.

Richard M. Scheffler, Timothy T. Brown, Brent D. Fulton, Stephen P. Hinshaw, Peter Levine, Susan Stone. Positive Association Between Attention-Deficit/Hyperactivity Disorder Medication Use and Academic Achievement During Elementary School. Pediatrics. 2009; 123 (5): 1273-9.

Blader JC, Pliszka SR, Jensen PS, Schooler NR, Kafantaris V. Blader et al. Stimulant-Responsive and Stimulant-Refractory Aggressive Behavior Among Children With ADHD. Pediatrics 2010; 126: e796.

Gadow KD, Nolan E, Sprafkin J, Sverd J. School observations of children with attention-deficit hyperactivity disorder and comorbid tic disorder: effects of methylphenidate treatment. J Dev Behav Pediatr. 1995; 16 (3): 167-76).

Gadow KD, Nolan EE, Sverd J, Sprafkin J, Paolicelli L. Methylphenidate in aggressive-hyperactive boys: I. Effects on peer aggression in public school settings. J Am Acad Child Adolesc Psychiatry. 1990; 29 (5): 710-8.

Taylor E, Dopfner M, Sergeant J, Asherson P, Banaschewski T, Buitelaar J, et al. European clinical guidelines for hyperkinetic disorder— first upgrade. Eur Child Adolesc Psychiatry 2004; 13(Suppl1): 17–30.

NICE clinical guideline 72. Attention deficit hyperactivity disorder. www.nice.org.uk/CG072.

Volkow ND, Wang GJ, Fowler JS, Telang F, Maynard L, Logan J et al. Evidence that methylphenidate enhances the saliency of a mathematical task by increasing dopamine in the human brain. American Journal of Psychiatry 2004; 161, 1173–1180.

Agencia Española del Medicamento y Producto Sanitario (AEMPS). http://www.aemps.gob.es/

Banaschewski T, Coghill D, Santosh P, Zuddas A, Asherson P, Buitelaar J et al. Long-acting medications for the hyperkinetic disorders. A systematic review and European treatment guideline. Eur Child Adolesc Psychiatry. 2006; 15 (8): 476-95.

Wigal, Sanchez, DeCory, D’imperio, Swanson. Selection of the optimal doses ratio for a controlled-delivery formulation of methylphenidate. The journal of applied research 2003; 3 (1).

Findling RL, Quinn D, Hatch SJ, Cameron SJ, DeCory HH, McDowell M. Comparison of the clinical efficacy of twice-daily Ritalin and oncedaily Equasym XL with placebo in children with Attention Deficit/Hyperactivity Disorder. Eur Child Adolesc Psychiatry. 2006; 15 (8): 450-9.

M.A. González, H.S. Pentikis, N. Anderl, M.F. Ben e dict, H.H. DeCory, S.J. Hirshey Dirksen et al. Methylphenidate bioavailability from two extended-release formulations. Int J Clin Pharmacol Ther. 2002; 40 (4): 175-84.

Swanson JM, Wigal SB, Wigal T, Sonuga-Barke E, Greenhill LL, Biederman J et al. A comparison of once-daily extended-release methylphenidate formulations in children with attention-deficit/hyperactivity disorder in the laboratory school (the Comacs Study). Pediatrics. 2004; 113 (3 Pt 1): e206-16.

Rothenberger A, Döpfner M. Editorial: Observational studies in ADHD: the effects of switching to modified-release methylphenidate preparations on clinical outcomes and adherente. Eur Child Adolesc Psychiatry. 2011; 20 Suppl 2: S235-42.

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