Olanzapine in the treatment of childhood-onset schizophrenia

Published

1998-09-30

How to Cite

Tomás, J., Bielsa, A., Teixido, M. L., Gastaminza, X., & Crespo, C. (1998). Olanzapine in the treatment of childhood-onset schizophrenia. Revista De Psiquiatría Infanto-Juvenil, (3), 207–209. Retrieved from https://aepnya.eu/index.php/revistaaepnya/article/view/461

Issue

Section

Book reviews

Authors

  • J. Tomás Hospital Infantil y Hospital de la Mujer Vall d'Hebron Barcelona
  • A. Bielsa Hospital Infantil y Hospital de la Mujer Vall d'Hebron Barcelona
  • M. L. Teixido Hospital Infantil y Hospital de la Mujer Vall d'Hebron Barcelona
  • X. Gastaminza Hospital Infantil y Hospital de la Mujer Vall d'Hebron Barcelona
  • C. Crespo Hospital Infantil y Hospital de la Mujer Vall d'Hebron Barcelona

Keywords:

Olanzapine, treatment

Abstract

Olanzapine is a potent 5-HT 2a / 2c antagonist, dopaminergic Dl, D2 and D4 with anticholinergic activity, that presents a profile whose affinity over receptors is similar to clozapine. S. Kumra, I.K. Jacobsen, (1998), have carried out a pilot study to examine the efficacy of olanzapine in schizophrenia beginning in childhood, when it appeared as refractory to the usual treatment.

Downloads

Download data is not yet available.

References

Beasley C, Tollestson G, Tran P, Salteries W, Sanger T, Hamilton S, (Olanzapine HGAD Study Group). Olanzapine versus placebo and haloperidol: acute phase results of de North American double-blind Olanzapine trial. Neuropsycho- pharmacol 1996;14:111-3. https://doi.org/10.1016/0893-133X(95)00069-P

Campbell M, Palig M. Subjective treatment Emergent Symptoms Scale (STESS). Psychofarmarcol Bull 1985;21:1063- 82. '

Jacobsen LK, Walker M, Edwards J, Chappell P, Woolston J. Clozapine in the treatment of a young adolescent with schizophrenia. J Am Acad Child Adolesc Psychiatry 1994; 33:645-50. https://doi.org/10.1097/00004583-199406000-00004

Kumra S, Frazier J, Jacobsen LK, et al. Chilhood-onset Schizoprenia: a double-blind clozapine-halopendol comparison. Arch Gen Psychiatry 1996;53:1090-7. https://doi.org/10.1001/archpsyc.1996.01830120020005

Kumra S, Jacobsen LK, Lenane M, Barbara MS, et al. Chilhood- onset Schizophrenia: An Open-Label Study of Olanzapine in Adolescents. J Am Acad Child Adolesc Psychiatry 1998; 37:(4). https://doi.org/10.1097/00004583-199804000-00015

Mozcs T, Toren P, Chernauzan N, et al. Cae study: clozapine treatment in very early onset schizophrenia. J Am Acad Child Adolesc Psychiatry 1994;33:65-70. https://doi.org/10.1097/00004583-199401000-00010

Orvaschel H, Tabrizi M, Chambers W. Schedule for affective disorders and Schizoprenia for School-age children Epidemiologic Version (Kiddic-SADS-E). 3a ed. Fort Lauderdale, FL: Nova University; 1980.

Rapoport J, Connors C, Rearing N. Rating scales and assessment instruments for use in pediatric psychopharmacology research. Psychopharmacol Bull 1985;21:1077-9.

Rapoport JL, Gield J, Kumra S, et al. Chilhood onset Schizophrenia: progressive ventricular change during adolescence. Arch Gen Psychiatry 1997;54:897-903. https://doi.org/10.1001/archpsyc.1997.01830220013002

Reich W, Weiner Z. DICA-RC (DSM-lll-R Version), revised version, V-R. St. Louis: Washington University; 1988.

Remselimidt H, Schulz E, Martin M, An open trial of clozapine in thirty-six adolescents with schizophrenia, J Child Adolesc Psychopharmacol 1994;4:31-41. https://doi.org/10.1089/cap.1994.4.31

Simpson G, Angus JSW. A rating scale for extrapyramidal side effects. Acta Psychiatr Scand 1970;212:9-11. https://doi.org/10.1111/j.1600-0447.1970.tb02066.x