Recurrent major depressive disorder in childhood and adolescence in treatment with Sertraline and Agomelatine
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Depression, childhood, adolescence, sertraline, agomelatineAbstract
It is now accepted that depression can also affect children and adolescents. Major depressive disorder (MDD) is a prevalent, familial recurrent illness that interferes significantly with the child’s normal development and is associated with increased risk for suicidal behaviors and psychiatric and psychosocial morbidity. Although most children and adolescents recover from the first depressive episode, 70% will experience one or more depressive recurrences. Recurrent depression represents a major target of suicide prevention. The priority is to treat first recurrent depression properly. We report the case of a female adolescent suffering recurrent depression in childhood and adolescence in maintenance antidepressant pharmacotherapy off-label with sertraline and agomelatine with full remission, recovery in 12 month follow-up assessment.
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