Autistic hebephrenia in 2023, regarding a clinical case

Published

2024-01-02

How to Cite

Ubiría , R., Andreu Gracia, H., Baldaquí, N., Díaz Téllez, C., Llobet Farré, M., & Morer Liñan, A. (2024). Autistic hebephrenia in 2023, regarding a clinical case. Revista De Psiquiatría Infanto-Juvenil, 41(1), 10–16. https://doi.org/10.31766/revpsij.v41n1a4

Issue

Section

Case reports

Authors

DOI:

https://doi.org/10.31766/revpsij.v41n1a4

Keywords:

Hebefrenia, diagnosis, psychopathology, schizophrenia, adolescents, children, early onset psychosis, neurodevelopmental disorders

Abstract

The clinical case of a 15-year-old male with a final diagnosis of schizophrenia is presented, through which an analysis of the fundamentals of classical psychiatry is carried out, particularly in relation to authors who phenomenologically approached psychosis cases initiated in youth, specifically hebephrenia. Although the concept of hebephrenia is no longer recognized as a separate subtype of schizophrenia in current classifications, the classical approach is examined to contextualize and substantiate the clinical approach to a recent case. The clinical characteristics of the classical concept of hebephrenia will be described, including early onset in puberty, the succession of oscillating affective states, rapid cognitive decline, and the presence of productive phenomena such as accessory delusions and hallucinations that change in relation to mood states. In addition, the autistic variant of hebephrenia is mentioned, characterized by isolation, apathy, brief and inadequate responses, lack of initiative, and depressive symptoms such as dysthymia with agitation. While it is important to bear in mind that the concept of hebephrenia is not recognized as a subtype in current classifications such as those of the DSM-5 or the ICD-11, this analysis allows us to understand historical perspectives and phenomenological approaches used in the past, which can assist us in the present.

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References

Kelleher I, Connor D, Clarke MC, Devlin N, Harley M, Cannon M. Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies. Psychol Med. 2012 Sep;42(9):1857-63. https://doi.org/10.1017/S0033291711002960 DOI: https://doi.org/10.1017/S0033291711002960

Remschmidt H, Theisen F. Early-onset schizophrenia. Neuropsychobiology. 2012;66(1):63-9. https://doi.org/10.1159/000339375. DOI: https://doi.org/10.1159/000338548

Hecker E. (1871). Die Hebephrenie: Ein Beitrag zur klinischen Psychiatrie. Archiv für Pathologische Anatomie und Physiologie und für Klinische Medizin, 52(2), 394–429. https://doi.org/10.1007/BF02329963 DOI: https://doi.org/10.1515/9783112391785-026

World Health Organization. (1992). The ICD-10 Classification of Mental and Behavioural Disorders: Clinical descriptions and diagnostic guidelines. Geneva: World Health Organization.

Peralta, V., Cuesta, M. J. (2001). How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainment. Schizophrenia Research, 49(3), 269–285. https://doi.org/10.1016/s0920-9964(00)00071-2 DOI: https://doi.org/10.1016/S0920-9964(00)00071-2

Vallejo Nágera J. A. Tratado de psiquiatría. Salvat, Madrid, 1945.

Jääskeläinen, E., Juola, P., Hirvonen, N., McGrath, J. J., Saha, S., Isohanni, M., ... & Miettunen, J. (2013). A systematic review and meta-analysis of recovery in schizophrenia. Schizophrenia bulletin, 39(6), 1296-1306. https://doi.org/10.1093/schbul/sbs130 DOI: https://doi.org/10.1093/schbul/sbs130

Rapoport JL, Giedd JN, Gogtay N. (2012). Neurodevelopmental model of schizophrenia: update. Molecular Psychiatry. https://doi.org/10.1038/mp.2011.153 DOI: https://doi.org/10.1038/mp.2012.23

Leonhard K. (1979). The classification of endogenous psychoses. Irvington. Fortschr Neurol Psychiatr. 1992 Aug;60(8):296-304. https://doi.org/10.1055/s-2007-999149. DOI: https://doi.org/10.1055/s-2007-999149

American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing, 2013. DOI: https://doi.org/10.1176/appi.books.9780890425596

Goldberg JF, Calabrese JR, Saville BR, Frye MA, Ketter TA, Suppes T, et al. ICD-10 diagnoses in 500 first-episode psychotic disorder patients. Journal of clinical psychiatry. 2009;70(4): 458-66. https://doi.org/10.4088/JCP.08m04381 DOI: https://doi.org/10.4088/JCP.08m04381

Clasificación Internacional de Enfermedades, undécima revisión (CIE-11), Organización Mundial de la Salud (OMS) 2019/2021, https://icd.who.int/browse11

Bleuler, E. (1911). Dementia Praecox or the Group of Schizophrenias. New York: International Universities Press. Schizophr Bull. 2011; 37(3): 471-9. https://doi.org/10.1093/schbul/sbr016. DOI: https://doi.org/10.1093/schbul/sbr016

Consorcio Centro de Investigación Biomédica en Red, M.P. (2015). Guía clínica y terapéutica para primeros episodios psicóticos en la infancia y adolescencia. CIBERSAM. https://www.ciberisciii.es/ficheros/SAM/Gu%C3%ADaPEPinfanciaAdolescencia_v5.0.pdf

Siskind D, McCartney L, Goldschlager R, Kisely S. Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis. Br J Psychiatry. 2016 Nov;209(5): 385-92. https://doi.org/10.1192/bjp.bp.115.177261 DOI: https://doi.org/10.1192/bjp.bp.115.177261

Pagsberg AK, Tarp S, Glintborg D, Stenstrøm AD, Fink-Jensen A, Correll CU, Christensen R. Acute antipsychotic treatment of children and adolescents with schizophrenia-spectrum disorders: a systematic review and network meta-analysis. Journal of the American Academy of Child & Adolescent Psychiatry. 2020;59(3): 353-66. https://doi.org/10.1016/j.jaac.2019.04.025 DOI: https://doi.org/10.1016/j.jaac.2019.04.025

Cohen D, Bonnot O, Bodeau N, Consoli A, Laurent C. Adverse effects of second-generation antipsychotics in children and adolescents: a Bayesian meta-analysis. Journal of Clinical Psychopharmacology. 2010;30(3): 253-60. https://doi.org/10.1097/JCP.0b013e3181d052b3

Schimmelmann BG, Walger P, Schultze-Lutter F. (2021). The Significance of At-Risk Symptoms.Can J Psychiatry. 2013;58(1): 32-40. https://doi.org/10.1177/070674371305800107 DOI: https://doi.org/10.1177/070674371305800107

Petrides G, Malur C, Braga RJ, Bailine SH, Schooler NR, Malhotra AK, Kane JM, Sanghani S, Goldberg TE, John M, Mendelowitz A. Electroconvulsive Therapy Augmentation in Clozapine-Resistant Schizophrenia: A Prospective, Randomized Study. Am J Psychiatry. 2015;172(1): 52-8. https://doi.org/10.1176/appi.ajp.2014.13060787 DOI: https://doi.org/10.1176/appi.ajp.2014.13060787

Walker EF, Bollini AM. Pubertal neurodevelopment and the emergence of psychotic symptoms. Schizophrenia Research. 2002;54(1-2):17-23. https://doi.org/10.1016/S0920-9964(01)00353-4 DOI: https://doi.org/10.1016/S0920-9964(01)00347-4

Salvatore P, Baldessarini RJ, Tohen M, Khalsa HMK, Sanchez-Toledo JP, Zarate C, Maggini C. McLean-Harvard International First-Episode Project: two-year stability. Schizophrenia Research. 2008;98(1-3): 6-15. https://doi.org/10.1016/j.schres.2007.08.019 DOI: https://doi.org/10.1016/j.schres.2007.08.019

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