Can a bacteria require psychotherapy?

Published

2025-09-20

How to Cite

Argüelles Balas, D., & Rodríguez-Quiroga, A. (2025). Can a bacteria require psychotherapy?. Revista De Psiquiatría Infanto-Juvenil, 42(3), 17–23. https://doi.org/10.31766/revpsij.v42n3a3

Issue

Section

Case reports

Authors

DOI:

https://doi.org/10.31766/revpsij.v42n3a3

Keywords:

tics, autoimmune diseases, obsessive-compulsive disorder, streptococcal infections, paediatrics

Abstract

Introduction: Neuropsychiatric symptoms in childhood pose a significant clinical challenge due to their emotional impact on families and the complexity of their diagnosis. Tics are particularly challenging because of their frequency and the wide range of potential underlying causes that must be considered. Among these, Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) remain a controversial entity, with diagnostic criteria still under review and no definitive consensus. Case report: This article presents the case of a child who experiences a sudden worsening of tic and associated neuropsychiatric symptoms, along with the most relevant clinical data supporting the diagnosis. Discussion and conclusion: This clinical case provides further evidence as to the potential existence of PANDAS as a differential diagnosis, highlighting the need for continued investigation into its mechanisms, validity and management in clinical practice.

Downloads

Download data is not yet available.

Author Biographies

Delia Argüelles Balas, Hospital Universitario Infanta Leonor

Servicio de Pediatría, Hospital Universitario Infanta Leonor. Facultad de Medicina, Universidad Complutense de Madrid, España.

Alberto Rodríguez-Quiroga, Hospital Universitario Infanta Leonor

Servicio de Psiquiatría, Hospital Universitario Infanta Leonor. Facultad de Medicina, Universidad Complutense de Madrid, España.

References

González Campillo T, López Laso E, Madruga Garrido M. Tics. Protoc diagn ter pediatr. 2022;1: 295-303. https://www.aeped.es/sites/default/files/documentos/29_0.pdf

Allen AJ, Leonard HL, Swedo SE. Case Study: A New Infection-Triggered, Autoimmune Subtype of Pediatric OCD and Tourette’s Syndrome. J Am Acad Child Adolesc Psychiatry. 1995;34(3): 307-11. https://doi.org/10.1097/00004583-199503000-00015

Swedo SE, Leonard HL, Garvey M, Mittleman B, Allen AJ, Perlmutter S, Dow S, Zamkoff J, Dubbert BK, Lougee L. Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections: Clinical Description of the First 50 Cases. Am J Psychiatry. 1998;155(2): 264-71. https://doi.org/10.1176/ajp.155.2.264

Esposito S, Bianchini S, Baggi E, Fattizzo M, Rigante D. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: an overview. Eur J Clin Microbiol Infect Dis. 2014;33: 2105-9. https://doi.org/10.1007/s10096-014-2185-9

Huey ED, Zahn R, Krueger F, Moll J, Kapogiannis D, Wassermann EM, Grafman J. A psychological and neuroanatomical model of obsessive-compulsive disorder. J Neuropsychiatry Clin Neurosci. 2008;20(4): 390-408. https://doi.org/10.1176/jnp.2008.20.4.390

Swedo ES. From Research Subgroup to Clinical Syndrome: Modifying the PANDAS Criteria to Describe PANS (Pediatric Acute-onset Neuropsychiatric Syndrome). Pediatr Ther. 2012;2(2): 1000113. https://doi.org/10.4172/2161-0665.1000113

Singer HS, Gilbert DL, Wolf DS, Mink JW, Kurlan R. Moving from PANDAS to CANS. J Pediatr. 2012;160(5): 725-31. https://doi.org/10.1016/j.jpeds.2011.11.040

LaRusso MD, Abadia CE. Symptom flares after COVID-19 infection versus vaccination among youth with PANS/PANDAS. Allergy Asthma Proc. 2023;44(5): 361-67. https://doi.org/10.2500/aap.2023.44.230049

Xie O, Davies MR, Tong SYC. Streptococcus dysgalactiae subsp. equisimilis infection and its intersection with Streptococcus pyogenes. Forrest GN, editor. Clin Microbiol Rev. 2024;37(3): e00175-23. https://doi.org/10.1128/cmr.00175-23

Marazziti D, Palermo S, Arone A, Massa L, Parra E, Simoncini M, Martucci L, Beatino MF, Pozza A. Obsessive-Compulsive Disorder, PANDAS, and Tourette Syndrome: Immuno-inflammatory Disorders. En: Kim Y-K, editor. Neuroinflammation Gut-Brain Axis Immun Neuropsychiatr Disord. Singapore: Springer Nature Singapore; 2023. p. 275-300. https://link.springer.com/10.1007/978-981-19-7376-5_13