Effectiveness of Lithium Treatment in Kleine-Levin Syndrome: A Case Report
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Copyright (c) 2025 Revista de Psiquiatría Infanto-Juvenil
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DOI:
https://doi.org/10.31766/revpsij.v42n2a5Keywords:
Klein-Levin Syndrome, disorders of excessive somnolence, lithiumAbstract
Introduction: This case describes a 14-year-old male patient diagnosed with Kleine-Levin Syndrome (KLS), who was attended by the Child and Adolescent Consultation-Liaison Psychiatry Team after presenting two episodes of hypersomnia and behavioral disturbances. Given the severity and recurrence of the episodes, a multidisciplinary approach was implemented, including discussions on differential diagnosis and consensus on therapeutic management. Case description: Due to the lack of response to conventional treatments, treatment with lithium carbonate was initiated, leading to a rapid remission of symptoms and the prevention of new episodes over a 12-month follow-up. The patient subsequently experienced a brief relapse with lower intensity and shorter duration, which was stabilized after adjusting the lithium dose. Discussion and conclusions: This case underscores the importance of a multidisciplinary approach in managing KLS, as well as the therapeutic potential of lithium for severe and refractory cases.
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